Chemistry Advances | ChemH.com

1 M Tris-HCl Buffer

How to Prepare 1 M Tris-HCl Buffer (pH 8.0)

Introduction Tris-HCl is a common buffer in molecular biology and biochemistry. It is used in protein, nucleic acid, electrophoresis, and enzyme workflows. Tris, or tris(hydroxymethyl)aminomethane, is a weak base. Its useful buffering range is about pH 7.0–9.0. This makes it…

Experimental CHD3 Base Editing: Delivery, Intended Correction, and Reported Outcome

Child Dies After Experimental Gene-Editing Treatment in China

A six-year-old girl died in Shanghai in March 2025, seven days after receiving an experimental gene-editing treatment intended to correct a rare mutation affecting brain development, according to a joint investigation published by Science and Retraction Watch on July 23,…

AI Steps Into Chemistry Labs

June 5, 2026 — In a first-of-its-kind test, researchers at Anthropic have put their AI, Claude, to the challenge of interpreting NMR spectra—one of chemistry’s most complex and time-consuming analytical tools. Traditionally, chemists painstakingly match peaks in a spectrum to…